Main

Kevin Stachelek


· Ph.D Candidate, University of Southern California
· stchlk.rbind.io ·
orcidID · Github · bluesky
Last updated on 2022-10-25


Education

PhD Candidate, Cancer Biology and Genomics

University of Southern California, Los Angeles, CA

hideme

2018 —

M.S. Translational Biotechnology

University of Southern California, Los Angeles, CA

hideme

2015

B.A. Biology

University of Southern California, Los Angeles, CA

hideme

2013

Professional Experience

Graduate Student Researcher

University of Southern California
PI: David Cobrinik

hideme

2018 —

Technician

Children’s Hospital Los Angeles
PI: David Cobrinik

hideme

2013 — 2018

Undergraduate Research Assistant

University of Southern California
PI: John Tower

hideme

2012 — 2013

Grant Support

NIH-NIDCD F31 DC019853-01: Ruth L. Kirschstein National Research Service Award

hideme

2021 — 2023

St. Baldrick’s

hideme

2021 — 2023

Scholarships and Awards

Undergraduate SOAR

hideme

2013

Publications

Li, H.-T., Xu, L., Weisenberger, D. J., Li, M., Zhou, W., Peng, C.-C., Stachelek, K., Cobrinik, D., Liang, G. & Berry, J. L. Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy. Nat Commun 13, 5523 (2022).

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Cambier, L., Stachelek, K., Triska, M., Jubran, R., Huang, M., Li, W., Zhang, J., Li, J. & Cobrinik, D. Extracellular vesicle-associated repetitive element DNAs as candidate osteosarcoma biomarkers. Sci Rep 11, 94 (2021).

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Kaneva, K., Merkurjev, D., Ostrow, D., Ryutov, A., Triska, P., Stachelek, K., Cobrinik, D., Biegel, J. A. & Gai, X. Detection of mitochondrial DNA variants at low level heteroplasmy in pediatric CNS and extra-CNS solid tumors with three different enrichment methods. Mitochondrion 51, 97–103 (2020).

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Berry, J. L., Xu, L., Kooi, I., Murphree, A. L., Prabakar, R. K., Reid, M., Stachelek, K., Le, B. H. A., Welter, L., Reiser, B. J., Chévez-Barrios, P., Jubran, R., Lee, T. C., Kim, J. W., Kuhn, P., Cobrinik, D. & Hicks, J. Genomic cfDNA analysis of aqueous humor in retinoblastoma predicts eye salvage: the surrogate tumor biopsy for retinoblastoma. Molecular Cancer Research 16, 1701–1712 (2018).

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Singh, H. P., Wang, S., Stachelek, K., Lee, S., Reid, M. W., Thornton, M. E., Craft, C. M., Grubbs, B. H. & Cobrinik, D. Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors. PNAS 115, E9391–E9400 (2018).

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Kim, J. W., Jacobsen, B., Zolfaghari, E., Ferrario, A., Chevez-Barrios, P., Berry, J. L., Lee, D. K., Rico, G., Madi, I., Rao, N., Stachelek, K., Wang, L.-C. & Gomer, C. Rabbit model of ocular indirect photodynamic therapy using a retinoblastoma xenograft. Graefe’s Archive for Clinical and Experimental Ophthalmology 255, (2017).

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Berry, J. L., Xu, L., Murphree, A. L., Krishnan, S., Stachelek, K., Zolfaghari, E., McGovern, K., Lee, T. C., Carlsson, A., Kuhn, P., Kim, J. W., Cobrinik, D. & Hicks, J. Potential of aqueous humor as a surrogate tumor biopsy for retinoblastoma. JAMA Ophthalmology 135, 1221–1230 (2017).

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Stachelek, K., Harutyunyan, N., Lee, S., Harutyunyan, A., Kim, J., Xu, L., Berry, J. L., Nagiel, A., Reynolds, C. P., Murphree, A. L., Lee, T. C., Aparicio, J. G. & Cobrinik, D. Non-Synonymous, synonymous, and non-coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression. Submitted.

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Shayler, D., Stachelek, K., Lee, S., Bai, J., Aparicio, J. G., Kim, Y., Singh, M., Bay, M., Thornton, M., Craft, C., Grubbs, B., Bonaguidi, M., Singh, H., & Cobrinik, David. Single cell transcriptomics reveals novel photoreceptor trajectories and a cancer-predisposed cone precursor state.

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Refereed Presentations

CBDI

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2022

BMM

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TSRI

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Keystone

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Software & Technology

SeuratTools

hideme

2022

Teaching

Introduction to R: Workshop for incoming PhD students - University of Southern California

hideme

2022

  • Led, organized, and co-designed 3-day workshop

Introduction to R: Workshop for incoming PhD students - University of Southern California

hideme

2021

  • Led, organized, and co-designed 3-day workshop